Hydrogen Inhalation and Heart Attack Recovery — What the First Human Pilot Found

A 2017 first-in-human pilot study in the Circulation Journal tested hydrogen gas inhalation during emergency stenting for ST-elevation myocardial infarction. The intervention proved feasible and safe in 20 patients, with an exploratory signal of improved left-ventricular reverse remodelling at 6 months — establishing the safety foundation for the larger trials needed to confirm clinical efficacy.